Ref Book- Bhaishajya Ratnavali 

Panchatikta Ghrita is an ayurvedic medicine in herbal ghee form. This medicine has ghee as it base. Panchatikta refers to five bitter herbs like neem, patola, vyaghri, guduchi and vasa which are main ingredient of this herbal ghee. Used for preparatory procedures for panchakarma also as medicine for skin diseases.